Evoluent Vertical Mouse VM4

Evoluent – world's first and original vertical handshake-grip mouse
Right-handed and left-handed models available

The shape is thoughtfully sculpted for uncompromised comfort and easy-to-reach programmable buttons. No finger contortions are needed to operate the buttons.

The thumb rest has been reshaped to provide even more comfort over earlier versions.

A new bottom thumb button provides greatly extended functionality when used with the included driver.

An extra-wide lip along the bottom edge prevents the little finger from rubbing the desk.

Evoluent VM4 has a special feature of horizontal scrolling. If you want to use it write us in which program (Microsoft Excel, Google Sheets) you want to take advantage of it and we will send you instructions concerned. 

Pointer speed controls on the side allow convenient adjustment without even releasing your grip from the mouse.

Top-mounted LEDs show through the chrome thumb rest to indicate selected pointer speed including extra low (XL), low (LO), MD (medium), to high (HI).

The logo is pure eye-candy. The illumination turns off when the system is in sleep mode to conserve notebook battery power.

Evoluent Mouse Manager for Windows provides extensive but easy-to-use functionality for 6 buttons through a simple and intuitive interface, see.

Ergonomic Benefits


Avoids forearm twisting for comfort and good health


The patented shape supports your hand in an upright neutral posture that generally avoids forearm twisting. Many users, including medical doctors, ergonomists, and physical therapists, said the Evoluent 

VerticalMouse provides superior comfort and even relieved their wrist pain.*


An approved mouse of University of California at Berkeley

The Evoluent VerticalMouse 2 (an earlier model identical in concept) was evaluated in 2007 by a team at the health services clinic in UC Berkeley, including medical doctors, physical therapists, ergonomists, and administrators. It was found to be comfortable, easily adapted to, and promote a neutral wrist and forearm posture. It was the only vertical type mouse approved for staff use within UC Berkeley and for sale in the campus store at that time. 

Evoluent is suitable for those allergic to rubber 

People allergic to rubber can use the Evoluent mice with no harm. There is no latex or rubber in the Evoluent mice. The scroll wheel, for example, is of silicone.


Evoluent mice have a guarantee of 2 years.


* The statements herein apply to some current or past users of Evoluent VerticalMouse, but since everyone is different, Evoluent makes no claim or representation that the Evoluent VerticalMouse will prevent, cure, or mitigate any medical condition, disease, injury, pain or discomfort for all users.


The VerticalMouse 4 has basic functionality without an additional driver. Additional drivers are used for programming the extra buttons.


  • Mac

  • Windows

    • Includes driver for Windows XP, Vista, Windows 7 in 32/64 bit and Windows 8/8.1 in 64 bit for programming all 6 buttons. The driver is not required for basic functionality. It can be downloaded here .

    • Freeware driver for other Windows versions at www.highrez.co.uk/downloads/XMouseButtonControl.htm (Evoluent has no business relationship with this vendor.)

    • USB only; not compatible with PS2 adapters. May be compatible with some USB KVM switches but it is not guaranteed.

  • Linux

    • Basic functionality without a driver

  • Unix

    • Compatibility unknown

Product code

11033 Evoluent VM4L, left, wired